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Abstract
BACKGROUND:
A familial and genetic predisposition for the development of rotator cuff tearing has been identified. The purpose of this study was to determine if a familial predisposition exists for healing after rotator cuff repair and if the reported significant association with a single-nucleotide polymorphism (SNP) in the ESRRB gene is present in patients who fail to heal.
CONCLUSIONS:
Individuals with a family history of rotator cuff tearing were more likely to have repair failures. Significant association of a SNP variant in the ESRRB gene was also observed with lateral failure.
Los individuos con una historia familiar de desgarro del manguito rotador eran más propensos a tener fallos de reparación. La asociación significativa de una variante de SNP en el gen ESRRB también se observó con insuficiencia lateral.
Copyright © 2016 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.
KEYWORDS:
ESRRB; Rotator cuff tear; familiality; genetic association; rotator cuff repair; tendon healing
- PMID: 27066960 [PubMed – in process]
